Villalobos faces one of their most challenging rescues when a house fire reveals a massive dog-hoarding situation. Two teachers fall in love with a deaf puppy they hope to give a forever home.

Mariah faces a challenging rescue when she realizes the dog in danger is deaf. Former adopters come back to Villalobos set on adopting a special needs dog. And the rescue struggles to track down a dog's owner because of outdated microchip information.

A senior dog is given a chance at a forever home. A rescue is complicated by the presence of two dogs. And the family discovers their personal dogs' origins when Tia surprises them with DNA test kits.

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A potential adopter wants to give a forever home to a senior dog that has only known life in a kennel. M2 and Kanani are shocked when they find a box of puppies in a field. And, Matt and Earl head to the kitchen to cook up some fresh food for a sick dog.

A potential best friend needs to pass a unique test before he can be adopted out. Parolee Jammall returns after a mysterious absence. A year after losing their house in a fire, M2 and Kanani do something special for the dog who saved their lives.

Tia and her kids race to rescue a stray dog near a dangerous, busy highway. An adoption requires some temperament testing in an 18-wheel truck when a trucker wants to adopt a dog to join him on the road. And, a return adopter seeks out a senior dog.

The Villalobos Rescue Center is the largest pit bull rescue in the USA, now located in New Orleans, LA. This show shows the interaction of the dog and man; About pets and people that no one wants.