After months of drug abuse Jackie hits rock bottom after her drug use results in someone's death and she decides to check into rehab. O'Hara has exciting news meanwhile All Saints is bought by a corporation who's new ER boss makes drastic changes to the hospital that makes the staff very unhappy.

Jackie detoxes in rehab and forges a surprising alliance with 17-year-old fellow addict Charlie. Director Cruz's innovations continue to irritate everyone on the All Saints staff except for Coop.

Worried about her daughter, Jackie leaves rehab early against her therapist's advice. Zoey has second thoughts about her relationship with Lenny.

Jackie learns that Grace knows the truth about rehab and races to tell Kevin before he hears about it from their daughter. She asks Charlie to meet her at an AA meeting but he shows up drunk.

Missing her family and adjusting poorly to single life, Jackie invites Kevin to meet her at a café for lunch. An attempted double suicide trauma case comes into the E.R. Zoey looks for a new roommate.

Jackie has a disturbing dream about using again. Zoey loses her engagement ring and questions her feelings for Lenny. O'Hara takes action on Jackie's behalf when Kevin sues for full custody.

Jackie covers for Cruz when he has a panic attack. Zoey surveys her coworkers for the best way to conduct a breakup. Akalitus enlists the staff in an elaborate charade when her mentor enters the hospital, suffering from dementia.

Jackie reveals her rehab stint to Cruz and Eddie offers support for Jackie's case during his deposition to Kevin's lawyer. O'Hara finally leans on Coop during an OB/GYN appointment.

The firing of her colleagues, Grace's refusal to go to school, and an overflowing emergency room full of patients redirected from another hospital push Jackie to finally seize control of the E.R. and run it her way.

Cruz purposely pushes Jackie to the breaking point, and then uses her reaction as grounds to fire her. Jackie enrolls Grace in public school. O'Hara goes into labor.