In the season 5 premiere, Billy and Jon Hamm take to the streets to find out if anyone will have a threesome with them! Later, Billy plays Immigrant or Real American? with Kevin the bisexual office manager. Plus, Billy plays the first For A Dollar, Quizzed in the Face and Lightning Round games of the new season!

In this week's jam-packed episode Billy hits the streets with Seth Rogen for a new segment called Death Rogen. Later, just in time for Thanksgiving, Billy and Sarah play What Does Michelle Rodriguez Bring to the Table? Finally, Annabelle the marketing intern competes in the very first Billy on the Street relay race! Other games include a new For A Dollar and Seth Vogue'n.

This week Billy is joined by Oscar winner Lupita Nyong'o for the brand new game Gay or Old? Later, everyone's favorite contestant Elena is back with a very patriotic Lightning Round! Finally, Lupita gets to work on her first half hour comedy special in a segment called Lupita Nyong'o: Bring the Pain. Other games include Barack Obama or Jennifer Lawrence? and Rizolli or Isles?

Billy Eichner quizzes people in the face for amazing gifts and money.

This week Billy is joined by Aziz Ansari to play the brand new game Is This a Kanye West Quote or Not? Later, Rachel Dratch is back for an exhilarating obstacle course, Escape Margot Robbie's Moment!

In this week's episode Billy is joined for the first time by a child actor, the star of Room, Jacob Tremblay! Together, Jacob and Billy take to the street for a brand new Lightning Round.

Billy and John Oliver take to the streets to find out if gay people care about him!

Billy takes the show on the road to LA with special guest James Corden! Emmy and Tony winner James Corden joins Billy as he desperately tries to appeal to the masses with Curbside Conga Line.

Billy is joined by Key and Peele star Keegan-Michael Key for the game Name 10 Gay People! Later, Billy is joined by aspiring actor Cameron to play Walking Dead or Talking Dead?