Iain's lack of attention towards a suicidal patient results in a serious disaster, endangering many lives.

Iain makes a shocking confession to Jan. The whole department struggle to come to terms with recent events. Ciara comes crashing back into Dylan's life.

Alicia returns to work earlier than planned. Dylan is tasked with clearing out Sam's locker. Eddie is brought to the stand to make his plea.

Iain and Dylan brawl on the day of Sam's funeral. Jacob and Blake remember Sam. Alicia treats a young patient with unexplained bruising.

Dylan panics when Ciara goes missing. Iain encounters a homeless Base. Ethan helps Alicia move on from her ordeal.

Dylan is dealt another blow by Ciara. Iain secures Base a place in Rehab. Blake searches for his grandmother.

Ruby and Iain face a shift from hell together. Duffy hides a diagnosis from Charlie, and confides in a old flame instead.

Jacob must face up to the past when his schizophrenic mother arrives at the hospital. Gem's jealousy gets the better of her. Iain struggles to control his emotions.

Dylan has gone missing, so David calls for back-up in his quest to find him. Rash reels from his split with Gem.

Dylan faces Ciara once again when she takes a turn for the worse. Louise's leadership style frustrates the nurses. An inspection team arrives at the ED.

Iain's mental health takes a sharp turn. Duffy is traumatised by her actions. Ethan and Alicia plot to reunite Rash and Gem.

Louise takes her chances on a slack nurse. Charlie remains suspicious of Duffy. Iain seeks help over his mental health.

Dylan and Ciara prepare to make their great escape. Duffy panics when Charlie answers her phone. Student nurse Marty is eager to please on his first shift.

Dylan aids the injured as Ciara becomes desperate to make her getaway. Jade takes things too far as she and Marty fight for a patient they both fancy.

Iain seeks comfort in Ruby after a difficult day. Duffy makes a shocking self-diagnosis after being admitted to the ED. Dylan pushes David away.

Charlie makes a shocking discovery. Alicia learns to trust her instincts. Marty tries to arrange a date with Joshua.

Dylan volunteers to work over the Christmas period. Noel is delighted to have hit his fundraising target.

Iain pushes Base away after being beaten up. Duffy asks Charlie to keep their break-up between them. Marty chooses his career over Jade.

Alicia learns the values of her own opinions. Duffy gets herself checked by a doctor. Marty and Jade spat over living arrangements.

Alicia makes a big career move. Marty's lies catch up with him. Elle hands the clinical lead status back to a returning Connie.

Iain finds himself in a quandary. Ruby and Gem search for a new place to live. Louise goes out of her way to help her patient.

Iain faces the consequences of his actions. Jan learns the truth about her son. Louise vows to stand up for her nurses when Jade is bitten by a patient.

Louise employs body cameras in a bid to protect the nurses. Connie isolates herself from the team. Gem helps Rash decide whether he wants to specialise in paediatrics or cardiology.

Louise fights for her nurses, and then hands in her resignation. Iain reaches out to a face from his past. A terrified Connie is unable to remember who assaulted her.

Iain contemplates about his life, believing he has taught Ruby all she needs to know. Marty plays counsellor for a gay couple.

Ruby makes a horrifying discovery. A cyber attack rocks Holby, affecting everyone. Connie clashes with Jac.

Gem must come to terms with the truth about Iain. A guilty Ruby goes out of her way for a patient.

New Registar Archie Hudson has a baptism by fire in Holby ED... while Duffy finally lets Charlie in on her secret

Medical relief Will makes quite the impression in the ED. Charlie pushes his nurses to the limit to hide Duffy's secret

Charlie snaps under the pressure of keeping Duffy's secret, Rash chooses Gem over traveling the world.

Connie comes face to face with her attacker in the ED. Duffy finally comes clean about her dementia diagnosis.

With Gem's help, Rash makes the choice to follow his dream of traveling. Will risks Connie's wrath to help a patient.

Iain faces a challenging day working in the emergency control centre.

Iain goes above and beyond on his first day back as a paramedic. Charlie steps on Duffy's toes trying to defend her right to work.

Will faces the biggest medical dilemma of his career when Toby returns to the ED.

Elle leaves Holby ED with her head held high. Ruby puts her foot down with Dani. Jacob makes a shocking discovery involving his mum.

The Holby ED is shaken up by the arrival of a brash new troubleshoooter , Ciaran. Jacob decides to fight to protect his mum. Iain steps up to support Jan.

An attempted mugging and motorcycle accident bring a number of casualties to the hospital, forcing Ruby to admit what's been going on with Dani and causing Jade to connect with a deaf patient.

Connie continues her downward spiral. Jacob is fighting to pull the wool from his mother's eyes.

Duffy decides to hang up her uniform. Jacob learns a truth from his past

Jacob says a final goodbye to Omo. A desperate Archie turns to Ciara's for help.

Iain gets embroiled in a tricky case with a familiar face while Jade gets more than she bargained for with Marty.

Connie takes the opportunity to prove herself, but it ends in disaster. Duffy proves her worth in the ED but gets caught in the middle of Connie's mistake.